Nutrients, Free Full-Text
Por um escritor misterioso
Last updated 23 maio 2024
The mesencephalic trigeminal nucleus (Mes5) processes oral sensory–motor information, but its role in the control of energy balance remains unexplored. Here, using fluorescent in situ hybridization, we show that the Mes5 expresses the melanocortin-4 receptor. Consistent with MC4R activation in other areas of the brain, we found that Mes5 microinjection of the MC4R agonist melanotan-II (MTII) suppresses food intake and body weight in the mouse. Furthermore, NTS POMC-projecting neurons to the Mes5 can be chemogenetically activated to drive a suppression in food intake. Taken together, these findings highlight the Mes5 as a novel target of melanocortinergic control of food intake and body weight regulation, although elucidating the endogenous role of this circuit requires future study. While we observed the sufficiency of Mes5 MC4Rs for food intake and body weight suppression, these receptors do not appear to be necessary for food intake or body weight control. Collectively, the data presented here support the functional relevance of the NTS POMC to Mes5 projection pathway as a novel circuit that can be targeted to modulate food intake and body weight.
Home Page: The American Journal of Clinical Nutrition
Nutritional Recommendations for Individuals with Diabetes - Endotext - NCBI Bookshelf
Black Survey Completer 2.0 Free - Colaboratory
Nutrients An Open Access Journal from MDPI
Dash.Js Error Type Download Id Manifest Message Unknown - Colaboratory
Nutrients, Free Full-Text
Health effects of dietary risks in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 - The Lancet
Nutrients, Free Full-Text
What is Food Nutrition Scale Data Entry? - ITS
Recomendado para você
-
Scp 096:SL Nextbot [Garry's Mod] [Mods]23 maio 2024
-
SCP-939 Poster for Sale by hanh5396523 maio 2024
-
SCP 464 Carbon Motor Brushes, Lot of 2 *FREE SHIPPING*23 maio 2024
-
SCP: Roleplay on X: Containment Breach Junk Section T by Kevinsaltsmhh. Sector-1 Checkpoint by Fighter_Lars. Really cool F3X builds by these two people, give them much love! They deserve it and everyone23 maio 2024
-
GARRY'S MOD - BUS EATER BUILDER VS BUS EATER (MONSTER) VS CAR EATER VS CARTOON CAT EATER VS TRAIN23 maio 2024
-
Oral-Fixation-Chihuahua of All Mechs by SpiderMilkshake -- Fur Affinity [dot] net23 maio 2024
-
SCP-096 Slaughter Fest!!! [SCP: Secret Laboratory]23 maio 2024
-
Soum..there's a hurricane coming23 maio 2024
-
George Larcombe BSc (Hons) posted on LinkedIn23 maio 2024
-
Dr.STONE Siren Head Plush Toys Limbs Movable Plush Toy23 maio 2024
você pode gostar
-
The Crew: Mission Deep Sea, Cooperative Family Card Game by Thames23 maio 2024
-
The World of Lucid Dreaming23 maio 2024
-
Sonic.EYX (Update 3) - Showcase - Fan Game23 maio 2024
-
OV Design Bonus #7 23 Aliens of Ben 23 by MrMustart on DeviantArt23 maio 2024
-
Naruto Manga Anime-Planet23 maio 2024
-
Menstruação atrasada é sinal de gravidez? - Mãe-Me-Quer23 maio 2024
-
Friday Hunt – Hunter X Hunter challenge week 30 - I drink and watch anime23 maio 2024
-
Spider-Man: Across the Spider-Verse release date delayed - GoldDerby23 maio 2024
-
Offline Dino, Nitro Wiki23 maio 2024
-
Corrida – Apps Android no Google Play23 maio 2024